LA 641 starts at
LA 44 (Jefferson Highway) in Lutcher and traverses north on Albert Street. It then crosses the
Illinois Central Railroad and goes eastward on West Main Street. LA 641 intersects Lutcher Avenue (
LA 3193) and North Airline Avenue (
LA 3274, which was formerly
LA 20). East of North Airline, the street is called East Main Street. Past Golden Grove Road, LA 641 resumes a north–south routing to meet
LA 3125 near the
Kansas City Southern Railway. The two highways are
concurrent for until LA 3125 ends at a junction with
LA 3213. From that ending, LA 641, traverses north, crossing the Kansas City Southern Railway and
Airline Highway (
U.S. Route 61) and traverses north through the
Maurepas Swamp. LA 641 ends at I-10 where it crosses the highway at milepost 194. LA 641 traverses a residential-commercial mix area in Lutcher and Gramercy, followed by an industrial area north of Gramercy. North of Airline Highway, the road traverses a secluded wetland before intersecting I-10. With the exception of the area immediately north and south of its intersection with Airline Highway, LA-641 is an undivided two-lane route in its entirety. It is a divided two-lane route in its short concurrency with LA 3125 and a four-lane road between LA 3213 and Airline Highway. ==History==