Susan Johns (1977–1979) Louisvilles first women's volleyball season came in 1977 under head coach Susan Johns. She held the job for 3 seasons finishing with a record of 28–60.
Scott Luster (1980–1984) Scott Luster was hired as the head coach in 1980. In 1982, he led the Cards to their first conference title in program history and first NCAA tournament berth. He would total two Metro Conference title and two NCAA tournament bids in 5 seasons at Louisville.
Bob McCarthy (1985–1987) Don Hardin (1988–1995) Don Hardin finished his tenure at Louisville as the most successful coach in program history and set the program up for its future success. He finished with an overall record of 192–76 after eight seasons at Louisville. He led the Cards to six regular season conference titles and six NCAA tournament berths.
Leonid Yelin (1996–2010) Leonid Yelin is the programs all-time winningest head coach. Under Yelin, the Cardinals won multiple CUSA regular season and tournament titles. In 1996, Louisville reached the Sweet Sixteen for the first time in program history. The Cards would reach the Sweet Sixteen a total four times in 1996, 1998, 2004, and 2005.
Anne Kordes (2011–2016) Following the retirement of Leonid Yelin in 2011, former Louisville player Anne Kordes was hired. In 2016, Kordes announced her resignation to spend more time with her family.
Dani Busboom Kelly (2017–2024) Dani Busboom Kelly was hired as the head coach at Louisville in 2017. Under Busboom Kelly, the program would reach new heights including reaching the first Elite Eight in program history and reaching the national championship twice. On January 29, 2025, she was hired by her alma mater to be the head coach of the
Nebraska Cornhuskers women's volleyball.
Dan Meske (2025–present) Following the departure of Dani Busboom Kelly, Dan Meske was hired as the head coach of Louisville. Meske was the associate head coach under Kelly since 2017. In 2022, he was name the
AVCA Assistant Coach of the Year. ==Season-by-season results==