In the 1996 comedy film
The Nutty Professor, Sherman Klump, under the guise of his alter ego Buddy Love, sings the first part of the song to his love interest Carla Purdy (while humorously twisting his rival Reggie Washington's hand to achieve the high singing note at the end of the chorus). In the 1997 comedy film
Vegas Vacation, Ellen Griswold and Wayne Newton sing the song in duet. In season 1 episode 4 of
South Park, "Big Gay Al's Big Gay Boat Ride", a bomb is armed to blow up the opposing football team using a sonic triggering device as Richard Stamos hits the high F-sharp note in the song. They attach the bomb to Middle Park's mascot. At halftime, Richard Stamos fails to hit the note, upsetting Jimbo and Ned, who shout that he is not as talented as his brother. At the end of the episode, Richard finally hits the high note causing
detonation. In the early 2000s,
Visa used a clip of the song in a TV commercial where the song was played during a
Pittsburgh Steelers game. To the dismay of many of the players and fans, in the middle of the commercial it cuts to a scene at a music store where an employee of the stadium sound crew was trying to buy a copy of "
Who Let the Dogs Out" by using a check. In the 2004 film
Johnson Family Vacation characters Dorothy Johnson and Destiny Johnson sing the tune in the bathtub In 2006, the
Disney film
The Wild features the song for a few seconds. In 2009, the music appeared in
OSS 117: Lost in Rio, a French comedy, the song was played for a few moments. In 2010, the
DreamWorks Animation film
Megamind, it is played a couple of times throughout the film. In 2019, it was used in the film
The Angry Birds Movie 2. Riperton's daughter
Maya Rudolph voiced Matilda in the film. In 1977
The Barron Knights use the song on one of their comic duel version, with someone firing at the birds in the trees. In 2025, the song was used in the first episode of the 7th season of
Black Mirror, "
Common People". In the 2007 movie Disturbia, the song is played by Shia LaBeouf’s character during a scene. ==Track listings==