Paganini is a youth exponent from
Frosinone Calcio. He made his first team debut on 18 December 2011 against
U.S. Siracusa in a
Lega Pro Prima Divisione game. He came in as an 89th-minute substitute for
Fabio Catacchini in a 1-0 away defeat. He was loaned out to
Fondi for six months from January 2013 until June 2013. He scored his first
Serie A goal on 18 October 2015 with
Frosinone after a 2–0 defeat of
Sampdoria. On 7 September 2020, he joined
Lecce. On 27 January 2022, he signed with
Ascoli until the end of the 2021–22 season. On 24 August 2022, Paganini signed a two-year contract with
Triestina. On 4 July 2024, he moved to
Vis Pesaro on a two-year deal. ==References==