St. Louis Cardinals Perdomo signed with the
St. Louis Cardinals as an international free agent in November 2010. He made his professional debut in 2011 with the
Dominican Summer League Cardinals. After spending 2012 and 2013 with Rookie League clubs, in 2014 Perdomo made 2 starts with the Low–A
New York–Penn League State College Spikes and 11 starts with the Single–A
Midwest League Peoria Chiefs, putting up a 4.43 ERA between the two levels. In 2015, Perdomo started the year with the Chiefs. He was named the Cardinals Minor League Baseball Pitcher of the Month for May, posting a 1.42 ERA and striking out 33 in innings. In July, he was the Cardinals representative at the
All-Star Futures Game, taking the place of the injured
Alex Reyes. After posting a 3.68 ERA in 17 starts with the Chiefs, Perdomo was promoted to the High–A
Palm Beach Cardinals in August, where he made 5 starts and had a 5.13 ERA.
San Diego Padres On December 10, 2015, Perdomo was selected by the
Colorado Rockies in the
Rule 5 draft, and subsequently traded to the
San Diego Padres in exchange for a
player to be named later or cash considerations. As a Rule 5 selection, Perdomo was added to the Padres bullpen for
2016 despite being hit hard in Spring Training and never having pitched above the High–A level. He was moved into the rotation in June as the Padres lost other starting pitchers to trades or injuries. On August 28, he threw his first
complete game, earning a 3–1 victory over the
Miami Marlins. Perdomo finished the season with a 9–10 record and a 5.71 ERA, although he improved over the season and had a better ERA as a starter (4.85) than as a reliever (9.10). Perdomo was named the Padres fifth starter coming out of Spring Training in
2017. After missing some time with a sore shoulder in April, Perdomo remained in the starting rotation for the remainder of the year. He posted an 8–11 record and a 4.67 ERA in 29 starts, with 118 strike-outs in innings pitched. He was 3rd on the club in innings pitched, behind
Clayton Richard and
Jhoulys Chacín, and led the National League in ground ball rate. Perdomo won a spot in the Padres' 2018 starting rotation. On April 11 of that year, in a game against the
Colorado Rockies, Perdomo threw a pitch behind
Nolan Arenado, causing Arenado to
charge towards Perdomo. Perdomo flung his glove at Arenado and dodged in a split second to avoid the tackle, leading to a bench-clearing brawl. On April 13, Perdomo was suspended for five games. He was placed on the disabled list on July 28 with a right shoulder strain. He ended the season 1–6 in 12 appearances (10 starts). He had an ERA of 7.05 in innings. In 2019, Perdomo pitched exclusively out of the bullpen, totaling 47 appearances while making just 1 start. He was 2–4 with an even 4.00 ERA. In mid-October 2020, Perdomo underwent
Tommy John surgery. On November 20, 2020, Perdomo was
designated for assignment by the Padres.
Milwaukee Brewers On December 16, 2020, Perdomo signed a minor league contract with the
Milwaukee Brewers organization. He did not play in a game in 2021 as he recovered from injury. He was assigned to the Triple-A
Nashville Sounds to begin the 2022 season. On May 6, 2022, Perdomo was selected to the 40–man and active rosters. In 14 appearances for Milwaukee, he posted a 3.80 ERA with 12 strikeouts in innings pitched. On November 18, Perdomo was non-tendered and became a free agent.
Chiba Lotte Marines On January 13, 2023, Perdomo signed with the
Chiba Lotte Marines of
Nippon Professional Baseball (NPB). The contract came with a $1.3 million guarantee and incentives that can boost the total to $1.8 million. In 53 appearances for the Lotte, he registered a 2.13 ERA with 41 strikeouts across innings of work. Perdomo became a free agent following the season.
Toros de Tijuana On February 8, 2024, Perdomo signed a minor league contract with the
Washington Nationals. He was released by Washington on March 21. On April 24, 2024, Perdomo signed with the
Toros de Tijuana of the
Mexican League. In 10 games for Tijuana, he recorded an 0.96 ERA with 7 strikeouts across innings pitched.
Orix Buffaloes On May 28, 2024, Perdomo signed with the
Orix Buffaloes of
Nippon Professional Baseball. On October 17, 2024, Perdomo re-signed with the Buffaloes for the 2025 season. ==See also==