De Vega was discovered in the
Palarong Pambansa () in the 1970s, and was recruited to be a part of
Far Eastern University Tamaraws varsity track team. She then became a member of the
Gintong Alay track and field program. She was coached by her father Francisco "Tatang" de Vega who was assisted by
Claro Pellosis. Santos Magno and
Anthony Benson later joined her training staff. In 1982, de Vega starred as herself in a film based on her own life titled
Medalyang Ginto (), directed by Romy Suzara and written by novelist
Edgardo M. Reyes. She signed a contract in the presence of 27-year-old
Philippine Olympic Committee president
Michael Marcos Keon, and received ₱35,000 for starring in the film. As Asia's sprint queen, she ran away with the gold medal in the
100-meter dash in the
1982 Asian Games in New Delhi She developed a
rivalry with Indian athlete
P. T. Usha. De Vega won the gold in the 100 meters at the SEA Games (
1987, 1991 and 1993). She also topped the 200 meter event in 1981, 1983, 1987 and 1993. She has twice won both the 100 and 200 meter golds in the
Asian Athletics Championships –
1983 and
1987. As a 16-year old in the 1981 edition, she placed second in the 400 meter run and also bagged the bronze medal in the 200 meters. De Vega was a two-time Olympian, represented the Philippines at the
1984 and
1988 Summer Olympics. She retired from her athletic career in 1994. ==Later life and death==