The first written mention of Lysice is from 1278. In 1316, it was bought by the Lords of Kunštát, who joined it to the
Kunštát estate and owned the village until 1520. In 1520–1529, it was a property of the
Pernštejn family. The next owners were the Černčický of Kácov family, who founded here a pond and started construction of a water fortress. Among the most notable owners were the Březnický of Náchod family, which held it in 1584–1678. During their rule, the fortress was finished and then rebuilt into a Renaissance castle. In 1652, Lysice was promoted to a
market town. ==Demographics==