Muthaiya moved to
Chennai from
Srivilliputhur in
Virudhunagar to make movies and debuted with the rural drama
Kutti Puli (2013) starring
Sasikumar. The film did not receive favorable reviews from the media but went on to perform well at the box office. Muthaiya moved on to make
Komban (2015), a story set in the
Ramanathapuram district starring
Karthi,
Lakshmi Menon, and
Rajkiran. The film is about an aggressive man (Karthi) and his relationship with his father-in-law (Rajkiran). Muthaiya, inspired by the egotistical tussles between his father and his grandmother, scripted the story straight from his own experiences. Following the success of
Komban, Muthaiya made
Marudhu (2016), featuring
Vishal and
Sridivya in the lead roles. The film received mixed reviews from critics but was a decent hit. In 2017, Muthaiya reunited with Sasikumar to make another rural drama film titled
Kodiveeran. Prior to the release of the film, the film's producer committed suicide due to financial problems. In January 2018, Muthaiya began work on
Devarattam, a second film with
Studio Green, which features a brother-sisters relationship with
Gautham Karthik in the lead role. The film released in 2019 to negative reviews but was still a hit. The film was an average rural action entertainer with routine elements that may have worked for audiences in
Madurai,
Tirunelveli, and surrounding areas. Muthaiya followed the same successful style in
Pulikkuthi Pandi (2021), which stars
Vikram Prabhu and
Lakshmi Menon comparing their previous film.
Pulikkuthi Pandi is Lakshmi Menon's third film under Muthaiya's direction, and the film also marks the actress's comeback to big screens after four years of film. In August 2022, Muthaiya's much expected
Viruman, the first time under the banner of
2D Entertainment was released. The film features
Karthi in the lead role, marking his second collaboration with Muthaiya, and was produced by
Suriya and
Jyothika.
Aditi Shankar, the daughter of Indian director
Shankar, made her acting debut as the female lead. In 2023, Muthaiya directed
Kathar Basha Endra Muthuramalingam, which saw him collaborating with
Arya for the first time. ==Filmmaking style==