MR10 is a liquid-fuel, upper-stage rocket engine in development by Avio on behalf of European Space Agency for use on Vega E. The engine is a derivative of the Russian RD-0146 engine and result of a past collaboration between Avio and Chemical Automatics Design Bureau (KBKhA) ended in 2014 after the start of the Russo-Ukrainian War and consequent economic sanctions. On May 6, 2022 engine testing campaign started at Salto di Quirra, Sardinia, with consequent maiden flight on a Vega E launcher expected by 2026 from Guiana Space Centre. The designation "M10" reflects key characteristics of the motor: "M" stands for "methane", referencing its liquid methane fuel; and "10" denoting the original target of 10 tonnes of thrust. The engine was renamed the MR10 in September 2024 in honour of the late Mikhail Rudnykh, who had served as Avio's head of cryogenic propulsion systems and led the engine's development.