In Greek mythology, Macistus or Makistos may refer to the following person and surname:Macistus, a Boeotian prince as the son of King Athamas probably by the cloud-nymph Nephele, thus the brother of Phrixus and Helle. From Macistus, the town of Macistus in Triphylia was believed to have derived its name. Makistios, an epithet of Heracles, who had a temple in the neighbourhood of the town of Macistus in Triphylia, Elis (Peloponnese).