The church was built in 1628 by the Roman humanist Giovanni Vittorio de Rossi within the wineyard he owned on the top of Monte Mario. In 1651 it was enlarged by the friars of the
Monastery of St. Onuphrius, to whom the ownership of the church had meanwhile passed; the works were commissioned to the architect Camillo Arcucci. After a period of abandonment, it was restored and enlarged again in 1726 by the architect
Filippo Raguzzini, who renewed the facade and interiors. After the ruins and abandonment caused by the
Napoleonic armies, the church was restored by
Pope Gregory XVI, who added the double flight of stairs. The church served as a parish from 1828 to 1904, while since 1931 the annexed convent hosts a community of cloistered
Dominican nuns. The church preserves the self-portrait of the Dominican nun
Anna Vittoria Dolara (1764–1827). ==Description==