Madrid–Cuenca–Motilla del Palancar–Valencia The first of this line are shared with the existing
Madrid–Seville high-speed rail line. The section onwards to Valencia was inaugurated on 15 December 2010 and entered service on 19 December 2010. Thirty trains run every day, fifteen in each direction. 22 are non-stop services and the remaining eight call at intermediate stations. Non-stop trains between Madrid and Valencia cover the in 1 hour and 40 minutes, saving two hours on the previous service of Alaris trains on the classic line. The line is built to , and electric powered at 25 kV AC, with signalling
ERTMS levels 1 and 2. During the 2007 works, the fossil site of
Lo Hueco,
Fuentes (Cuenca), was discovered. More than 10 000 fossils have been collected, almost half of which belong to
titanosaurs comprising more than twenty sets of partial skeletons in anatomical connection or with a low dispersion of their skeletal elements.
Valencia–Castellón This segment was inaugurated on 22 January 2018 and is a part of the Mediterranean Corridor. With this extension to
Castellón a new AVE service Madrid-Castellón was introduced which cut the journey time between the two cities by further 30 minutes to total 2 hours and 25 minutes. Four AVE trains per day are scheduled, two in each direction between Madrid and Castellón while this segment is also used by the
Alvia service Gijón–Castellón.
Valencia–Xàtiva This segment is under construction and planned for mixed use (goods and passengers). The 52 km part between Torrent outside Valencia and
Xàtiva, which is under construction since October 2002, was initially expected to be completed by end 2020 and it is designed for speeds up to 350 km/h.
Xàtiva–Nudo de La Encina Since 9 September 2023 this segment is closed for modernisation works to high-speed rail standards. All traffic in this segment is now routed via the conventional Iberian-gauge line between Xàtiva and La Encina Hub. Those modernization works including conversion to standard-gauge high speed line were initially expected to be completed by end 2022 and with additional works for adding a double track in the same section, those are now expected to be finished by middle 2025 at latest.
Motilla del Palancar–Albacete A segment between Cuenca and Albacete provinces. This section was inaugurated on 15 December and open to the public on 19 December 2010.
Albacete–Nudo de La Encina–Monforte del Cid–Alicante The section from Albacete to Alicante opened in June 2013.
Monforte del Cid–Elche–Murcia–Cartagena The segment between the municipality of Monforte del Cid in Alicante and
Murcia has a length of , of which are located in the province of Alicante and the remaining in Murcia. It is a new segment of double track in standard gauge, suitable for speeds up to . The long access section towards the new segment to Murcia had been in service since 2008, and was only used for Iberian gauge trains until 1 February 2021, when the section linking Monforte del Cid, Elche and Orihuela - in total length - was inaugurated. The continuation of the line up to Murcia put in service on 20 December 2022. This section is fitted with three track rails, two of standard gauge and one of Iberian gauge.
Murcia–Almería The main purpose of this line is to connect the Transversal Rail Line to the Madrid-Levante and Mediterranean Corridor rail lines. This segment is ( in
Almería Province and in
Murcia Region). == Stations ==