Karimi started her career as an
air hostess, and later quit that job to pursue a career in modelling. In 2010, after working on various international modelling projects, she came to
Mumbai for three months on a modelling contract. In February 2015, she made a guest appearance in the film
Roy. Karimi was a contestant in the reality TV show,
Bigg Boss 9, where a group of celebrities from various walks of life live together in a large house. One of the contestants is eliminated every week, based on public votes. The show went on air in October 2015 on Colors. She was one of the three finalists of the season and ended up as a runner-up. In 2018, she joined
Star Plus's
Ishqbaaaz as Nancy. In October 2018, Karimi accused Umesh Ghadge the director of
Kyaa Kool Hain Hum 3 of sexual harassment. She had also accused director
Sajid Khan of sexual harassment at the time and expressed her intention to quit
Bollywood after Khan appeared as contestant on
Bigg Boss 16 in 2022. Mandana participated in an Indian TV reality show called
Lock Upp. == Personal life ==