Mao Muzhi's father was Mao Bao, a distinguished general. His given name underwent many changes in his later years. First, he changed his given name to his style name Xianzu (憲祖) in 361 due to taboo as
Emperor Ai of Jin's wife, was named
Wang Muzhi. As Huan Wen rose to power and slowly took control of the state, Mao went through another name change due to taboo again, as Huan Wen's mother's given name was 'Xian (憲)'. This time, he used his childhood name, 'Husheng (虎生)' Mao Muzhi first served in the staff of Yu Yi, who at the time was busy preparing invasions against
Cheng Han and
Later Zhao. His brother
Yu Bing died in 344, and with no one else in the Yu clan to handle home affairs, Yu Yi chose his son Yu Fangzhi (庾方之) to guard
Xiangyang. However, Fangzhi was too young, so Yu Yi entrusted Muzhi, to be Fangzhi's marshal. Yu Yi died the following year in 345 from an ulcer, which led to many among his staff led by Gan Zan (干瓚) to mutiny. Mao Muzhi,
Yuan Zhen, Jiang Bin (江虨) and Zhu Dao (朱燾) joined forces and put down Gan Zan's rebellion. After the death of Yu Yi, Mao Muzhi went to serve Huan Wen, who in 345 became Inspector of
Jingzhou. Mao Muzhi participated in Huan's second northern expedition in 356 serving as Administrator of
Yingchuan. After Huan Wen captured
Luoyang, Mao Muzhi was left to guard Luoyang while they wait for
Xie Shang's arrival. In 369, Mao Muzhi, now Mao Husheng, was involved in Huan Wen's third northern expedition to destroy
Former Yan. Husheng was serving as Huan Wen's Champion General and was tasked in building a canal at
Juye to allow water to flow from the
Wen River to the
Qing River. After Huan Wen was badly defeated at
Fangtou, Husheng was appointed Chief Controller of four commanderies, and as Administrator of Eastern Yan. He was further made Administrator of
Huainan to defend
Liyang when
Yuan Zhen's Rebellion broke out shortly after the defeat at Fangtou. After Huan Wen deposed Emperor Fei in 371, Mao Husheng was made Chief Controller in Jingzhou north of the
Mian River and in
Yizheng in
Yangzhou. His brother, Mao Anzhi (毛安之) also played an important role in Huan Wen's government, tasked in defending the palace with his guards. == Defense against Former Qin ==