Herndon started her career as an assistant professor at the
University of Texas at Austin in 1971. She taught ethnomusicology and anthropology at the university for seven years. While teaching in Texas, Herndon developed a course which returned to her roots in country music and examined the genre from an anthropological perspective. Students of the course looked at how country music was viewed culturally as music of white, unsophisticated and lower-class people, even for those who gained fame. It also examined how the genre was used as a gateway for singers like
Charley Pride and
Johnny Rodriguez to gain acceptance in white society. Wanting to create a venue which would support independent scholarship without censorship in ethnomusicological research, in 1984, she founded the Music Research Institute, in
Hercules, California. She encouraged research into issues such as the demise of American community orchestras, censorship of lyrics, and the effects to hearing caused by amplified sound. Her activism and support of alternative research led to a fissure with the university and she left in 1985. Herndon continued working at the Music Research Institute, expanding it from its location in the
San Francisco Bay Area by creating branches in
Richmond, California and
Hyattsville, Maryland. In 1987, she became the co-chair of the International Council for Traditional Music’s Music and Gender Study Group, introducing interdisciplinary studies on the cultural construction of gender and its impacts on music and performance. In 1989, Herndon, who had a history of
lupus, had a stroke, which resulted in deafness in one ear and left her with sensitivity in her feet. Despite these health issues, in 1990 she became a professor in the division of Musicology and Ethnomusicology at the School of Music at the
University of Maryland. At the same time, she served as an affiliate of the
Women's Studies Department. Herndon remained active, in spite of a subsequent cancer diagnosis, hosting the international conference, "Gender and the Musics of Death" for the Music and Gender Study Group of the International Council for Traditional Music. The event was hosted at the University of Maryland in November 1996. ==Community involvement==