During her teens, de Dominici studied under the painter and sculptor
Mattia Preti, who was painting and sculpting the interior of
St. John's Co-Cathedral in
Valletta at the time. She is believed to have contributed, and is specifically recorded as assisting Preti on his best known work, a series of paintings depicting the life and martyrdom of
St John the Baptist (1661–1666), which decorates the vaults of the co-Cathedral. She was a strong-minded and versatile person; characteristics clearly seen in the two wills she drafted. Giovannantonio Ciantar's
Malta Illustrata (1772) paints a picture of a person who knew what she wanted to do with her life from a young age: "[Maria showed a] repugnance to apply her energies to female duties and was thus often rebuked by her parents ... She would do nothing other than draw figures and other things according to her whim and natural talents. At last her parents, seeing her so inclined and disposed to painting, provided an art master to teach her design." Being a
Carmelite tertiary
nun, she was free to live outside the convent walls and away from the constraints of family ties. It appears that she was a quick study who flourished under Preti's tutelage. Giovannantonio Ciantar observes that "under his [Preti's] direction she worked well and as he was painting the ceiling of the Church of St John he allowed her to paint some of the female figures; in doing this she succeeded almost more felicitously than the master." This is further corroborated by Giuseppe Maria de Piro's account in
Squarci di Storia (1839): "[She] superseded any other of his pupils, so much so that the celebrated master chose her to collaborate with him in painting the great vault of the Church of St John, in which the female figures were, to a great extent, executed by her." In 1682, de Dominici left Malta, probably with the entourage of the Grand Master's nephew and his wife Isabella d'Avalos d'Aquino d'Aragona, who, together with her master Preti, encouraged the artist to spread her wings abroad. She eventually had her own studio in
Rome, where she began to receive sculpture and painting commissions thanks to
letters of introduction from the Grand Master. In Rome, she lived with a woman companion at her studio near
San Giovanni dei Fiorentini. ==Works==