Weeden was born July 6, 1846, in
Huntsville, Alabama, six months after the death of her father, Dr. William Weeden, who had also been a prosperous planter. Her mother was his second wife, the former widow Jane (née Urquhart) Watkins. Weeden and her five older siblings were raised by their mother in the
Weeden House in Huntsville. During the Civil War, the Union Army took over their house for use by its officers when it occupied the city in 1862. The family first moved to the slave quarters. When Jane, one of the older Weeden daughters, was attending college in
Tuskegee, Alabama, the mother moved the rest of the family there. Maria Weeden also attended the same school,
Tuskegee Female College during the war years. (It later became known as
Huntingdon College.) She had written poetry and painted since childhood, and at college studied with painter
William Frye. After returning to Huntsville, Weeden began to paint cards, booklets, dinner cards, and small gifts to sell to help her family. Some were watercolors of flowers and landscapes. She also taught art classes. ==Career==