Early explanations for the population decline of the Indigenous peoples of the Americas include the brutal practices of the Spanish
conquistadores, as recorded by the Spaniards themselves, such as the
encomienda system, which was ostensibly set up to protect people from warring tribes as well as to teach them the Spanish language and the
Catholic religion, but in practice was tantamount to
serfdom and
slavery. The most notable account was that of the
Dominican friar Bartolomé de las Casas, whose writings vividly depict Spanish atrocities committed in particular against the
Taínos. The second European explanation was a perceived divine approval, in which God removed the Indigenous peoples as part of His "divine plan" to make way for a new Christian civilization. Many Native Americans viewed their troubles in a religious framework within their own belief systems. According to later academics such as
Noble David Cook, a community of scholars began "quietly accumulating piece by piece data on early epidemics in the Americas and their relation to the subjugation of native peoples." Scholars like Cook believe that widespread epidemic disease, to which the Indigenous peoples had no prior exposure or resistance, was the primary cause of the massive population decline of the Native Americans. One of the most devastating diseases was smallpox, but other deadly diseases included
typhus,
measles, influenza,
bubonic plague,
cholera,
malaria,
tuberculosis,
mumps,
yellow fever, and
pertussis, which were chronic in Eurasia. However, recently scholars have studied the link between physical colonial violence such as warfare, displacement, and enslavement, and the proliferation of disease among Native populations. For example, according to
Coquille scholar
Dina Gilio-Whitaker, "In recent decades, however, researchers challenge the idea that disease is solely responsible for the rapid Indigenous population decline. The research identifies other aspects of European contact that had profoundly negative impacts on Native peoples' ability to survive foreign invasion: war, massacres, enslavement, overwork, deportation, the loss of will to live or reproduce, malnutrition and starvation from the breakdown of trade networks, and the loss of subsistence food production due to land loss." Further,
Andrés Reséndez of the
University of California, Davis points out that, even though the Spanish were aware of deadly diseases such as smallpox, there is no mention of them in the New World until 1519, implying that, until that date, epidemic disease played no significant part in the depopulation of the
Antilles. The practices of forced labor, brutal punishment, and inadequate necessities of life, were the initial and major reasons for depopulation. In this way, "slavery has emerged as a major killer" of the Indigenous populations of the Caribbean between 1492 and 1550, as it set the conditions for diseases such as smallpox, influenza, and malaria to flourish. Unlike the populations of Europe who rebounded following the
Black Death, no such rebound occurred for the Indigenous populations. He also wrote: In contrast, historian
Russel Thornton has pointed out that there were disastrous epidemics and population losses during the first half of the sixteenth century "resulting from incidental contact, or even without direct contact, as disease spread from one American Indian tribe to another." Thornton has also challenged higher Indigenous population estimates, which are based on the Malthusian assumption that "populations tend to increase to, and beyond, the limits of the food available to them at any particular level of technology." The European colonization of the Americas resulted in the deaths of so many people it contributed to
climatic change and temporary
global cooling, according to scientists from
University College London. A century after the arrival of
Christopher Columbus, some 90% of Indigenous Americans had perished from "wave after wave of disease", along with mass
slavery and war, in what researchers have described as the "great dying". According to one of the researchers, UCL Geography Professor
Mark Maslin, the large death toll also boosted the economies of Europe: "the depopulation of the Americas may have inadvertently allowed the Europeans to dominate the world. It also allowed for the Industrial Revolution and for Europeans to continue that domination."
Biological warfare When Old World diseases were first carried to the Americas at the end of the fifteenth century, they spread throughout the southern and northern hemispheres, leaving the Indigenous populations in near ruins. No evidence has been discovered that the earliest Spanish colonists and missionaries deliberately attempted to infect the American Natives, and some efforts were made to limit the devastating effects of disease before it killed off what remained of their labor force (compelled to work under the
encomienda system). Many of the instances likely went unreported, and it is possible that documents relating to such acts were deliberately destroyed, By the middle of the 18th century, colonists had the knowledge and technology to attempt biological warfare with the smallpox virus. They well understood the concept of quarantine, and that contact with the sick could infect the healthy with smallpox, and those who survived the illness would not be infected again. Whether the threats were carried out, or how effective individual attempts were, is uncertain. One such threat was delivered by fur trader
James McDougall, who is quoted as saying to a gathering of local chiefs, "You know the smallpox. Listen: I am the smallpox chief. In this bottle I have it confined. All I have to do is to pull the cork, send it forth among you, and you are dead men. But this is for my enemies and not my friends." Likewise, another fur trader threatened
Pawnee Indians that if they didn't agree to certain conditions, "he would let the smallpox out of a bottle and destroy them." The Reverend
Isaac McCoy was quoted in his
History of Baptist Indian Missions as saying that the white men had deliberately spread smallpox among the Indians of the southwest, including the Pawnee tribe, and the havoc it made was reported to General Clark and the Secretary of War. Artist and writer
George Catlin observed that Native Americans were also suspicious of vaccination, "They see white men urging the operation so earnestly they decide that it must be some new mode or trick of the pale face by which they hope to gain some new advantage over them." So great was the distrust of the settlers that the Mandan chief
Four Bears denounced the white man, whom he had previously treated as brothers, for deliberately bringing the disease to his people. During the
siege of British-held
Fort Pitt in the
Seven Years' War, Colonel
Henry Bouquet ordered his men to take smallpox-infested blankets from their hospital and gave them as gifts to two neutral
Lenape Indian dignitaries during a peace settlement negotiation, according to the entry in the Captain's ledger, "To convey the Smallpox to the Indians". In the following weeks,
Sir Jeffrey Amherst conspired with Bouquet to "Extirpate this Execreble Race" of Native Americans, writing, "Could it not be contrived to send the small pox among the disaffected tribes of Indians? We must on this occasion use every stratagem in our power to reduce them." His Colonel agreed to try. In Brazil, well into the 20th century, deliberate infection attacks continued as Brazilian settlers and miners transported infections intentionally to the Native groups whose lands they coveted.
Vaccination After
Edward Jenner's 1796 demonstration that the
smallpox vaccination worked, the technique became better known and smallpox became less deadly in the United States and elsewhere. Many colonists and Natives were vaccinated, although, in some cases, officials tried to vaccinate Natives only to discover that the disease was too widespread to stop. At other times, trade demands led to broken quarantines. In other cases, Natives refused vaccination because of suspicion of whites. The first international healthcare expedition in history was the
Balmis Expedition which had the aim of vaccinating Indigenous peoples against smallpox all along the
Spanish Empire in 1803. In 1831, government officials vaccinated the
Yankton Dakota at
Sioux Agency. The
Santee Sioux refused vaccination and many died. ==Depopulation by European conquest==