On February 23, 1958, the
New York Daily News chose Chris as that week's "Typical American Girl." Her photo appeared in the Sunday magazine section and she won a $25 prize. She appeared in productions for the theatre, including
Many Loves,
Women of Trachis,
In the Jungle of Cities,
The Apple, and
Man is Man. Prompted by the discovery that her birth name was already registered with
Actors Equity, Miller devised a stage name simply by shortening her then-married name, Christopoulos. In 1965, Chris was an under study for the roles of Agnes Graham and Sylvia Goldman in the original Broadway production of
The Family Way. In 1967, she was a stand by for the roles of Lulu and Meg in
The Birthday Party on Broadway. In 1968, she was a stand by for the title role in a Broadway production of
The Seven Descents of Myrtle. Chris appeared in the romantic drama film
John and Mary (1969), co-starring with
Dustin Hoffman. In 1970, she guest starred on
Hawaii Five-O. The same year, she played Myrtle Young in the crime film
The Honeymoon Killers. She also had a role in the drama film
The People Next Door. Chris appeared on Broadway in
Lenny. She was cast as Naomi, the paranoid mother of
Allen Ginsberg in
Kaddish. The play opened at the
Brooklyn Academy of Music in February 1972. Chris won an
Obie Award for her performance. She also won a
Drama Desk Award, an
Outer Critics Circle Award and a
Variety Critics Poll. The character opened a restaurant called Heavenly Hash in the fictional city of Llanview. Chris played Mrs. Bingham in the comedy film
Rhinoceros (1974), co-starring with
Gene Wilder. In July 1974, she co-starred with
Lee Wallace in the musical
Laugh a Little, Cry a Little at the Westbury Music Fair. She played Faye Stone in the television film
Strike Force (1975), co-starring with
Richard Gere. In 1976, Chris left her role on
One Life to Live. Chris guest starred on
Rafferty and
Barney Miller. She played Harriet in the television film
Some Kind of Miracle (1979). The same year, she appeared in the television miniseries
Backstairs at the White House. She made guest appearances on
Family and
Kaz. The same year, she also appeared in the romantic comedy film
Loving Couples. She had a role in the television film ''
The Secret War of Jackie's Girls. In 1980, Chris returned to the role of Wanda on One Life to Live
. She co-starred with her husband, Lee Wallace, in the television film A Doctor's Story
(1984). She guest starred on Fame
in 1986. In 1990, she co-starred with Lee Wallace in Taking Stock
for the Jewish Repertory Theatre. In October 1992, she co-starred with Lee Wallace in God of Vengeance for the Jewish Repertory Theatre. Soap Opera Digest reported in January 1994 that Chris would be leaving her role on One Life to Live''. Her final air date was February 7, 1994. In the 1990s, she made guest appearances on
Law & Order. In 1997, she appeared in the television film
Joe Torre: Curveballs Along the Way. The same year, she also had a role in the film
The Deli. In May 1997, Chris played Faye in
The Young Girl and the Monsoon at
Playwrights Horizons. Chris guest starred on
Third Watch in 1999. She appeared as Mrs. Chadwick in the comedy film
Waltzing Anna (2006). Chris guest starred on
Law & Order: Special Victims Unit and
Law & Order: Criminal Intent. She played Elizabeth Robbins in the suspense film
Altered Minds (2013). In July 2024, Chris played serial killer
Nannie Doss in a solo reading of
The Giggling Granny at the Southampton Cultural Center. ==Personal life==