In 1995, Tabassum founded URBANA, an architecture practice based in Dhaka, Bangladesh with
Kashef Chowdhury. The firm designed a number of projects for about ten years. In 2005, Tabassum established Marina Tabassum Architects, and she serves as its principal architect. Tabassum designed the Bait Ur Rouf Mosque in Dhaka, completed in 2012. She won her first
Aga Khan Award for Architecture for this project in 2016. As of 2025, Tabassum is a professor of Architectural Design for Climate Adaptation at the Department of Architecture at
Delft University of Technology, Netherlands. She held the Gehry Chair at the
University of Toronto during 2022–2023. Tabassum chairs Foundation for Architecture and Community Equity (F.A.C.E) and Prokritee, a fare trade organization. She is a fellow of the
Royal Society of Arts (RSA). ==Notable works==