Early works Del Castillo made her acting debut in 1978 when she took part in a film called
The Last Escape. She became well known in 1991 when she starred as Leticia in
Muchachitas, a
telenovela airing in several
Latin American countries. The following year, she went to star in
Mágica juventud. Her other leading roles in 1990s was in
Azul (1996), long-running
Alguna vez tendremos alas (1997), and
La mentira. In 1995 she appeared in the music video "
Fuego de Noche, Nieve de Día" by
Ricky Martin. In early 2000s, Del Castillo played the leading roles in telenovelas
Ramona (2000),
El derecho de nacer (2001) and
Bajo la misma piel (2003-2004). In 2003, she made her American television debut playing a recurring role in the
PBS drama series
American Family starring
Edward James Olmos and
Sônia Braga. In 2009, she had a recurring role in the Showtime dark comedy-drama
Weeds playing Pilar Zuazo, a powerful woman in Mexican politics. In 2002 and 2003, she embarked on an international tour alongside
Argentine actor
Saul Lisazo with the play
Cartas de Amor (
Love Letters). In 2005, she starred alongside
Demián Bichir in the romantic comedy film
American Visa. In 2006, Del Castillo starred in the film
Bordertown, which became her first role in Hollywood. In 2007, she went to star in the drama film
Under the Same Moon directed by
Patricia Riggen. The film grossed $23.3 million against $1.7 million budget. She also starred in a number of independent movies, include
The Black Pimpernel (2007) and
Julia alongside
Tilda Swinton. In November 2007, Del Castillo was named one of the "Stars of the Year" and in 2011 one of the "25 most influential women" and "50 most beautiful" by
People en Español magazine. In 2009, del Castillo was appointed Ambassador for the
Mexican Commission on Human Rights and the following year she helped launch the
Blue Heart Campaign in order to raise awareness and fight human trafficking.
2011–present In 2011, Del Castillo starred as Teresa "La Mexicana" Mendoza in the
Telemundo telenovela
La reina del sur based on a novel of the same name by Spanish author
Arturo Pérez-Reverte, a role that skyrocketed her fame across Latin America. With a $10 million budget it is the second most expensive telenovela ever produced by Telemundo. The series later was renewed for a second season, that premiered in 2019. del Castillo continued her collaboration with
Telemundo in 2015, starring in
Dueños del Paraiso. The telenovela is inspired by the drug trade of Miami in the 1970s. She also appeared in a number of American television shows, include
CSI: Miami,
Grimm and
Dallas. In 2015, she had a recurring role as Rogelio de la Vega's ex-wife in the CW comedy series,
Jane the Virgin. On November 20, 2015, Del Castillo launched a new brand of tequila named
Honor del Castillo in association with the Vivanco Family. She serves as the spokesperson for the brand. Del Castillo has also appeared in advertising campaigns for
L'Oréal and
Ford. In 2012, Del Castillo starred in the Mexican film
Colosio: El asesinato, which centers around the assassination of the Mexican presidential candidate
Luis Donaldo Colosio. The following year, she starred in the American prison drama film
K-11. In later years, Del Castillo appeared in many American movies, including playing
Idris Elba's ex in the 2014 thriller
No Good Deed,
Antonio Banderas' wife in the disaster-survival drama
The 33,
All About Nina (2018),
El Chicano (2019), and
Bad Boys for Life (2020). In 2017, she went to star in the
Netflix political thriller series,
Ingobernable playing the fictional First Lady of Mexico, Emilia Urquiza. The second season premiered in 2018. In 2019, del Castillo made her off-Broadway debut in the Audible Theater production of
Isaac Gomez's play
The Way She Spoke. The performance earned her
Drama Desk,
Drama League, and
Lucille Lortel Award for Outstanding Lead Actress in a Play nominations, making her the first Mexican actress to be nominated for three theatre awards in New York. In 2022, del Castillo starred in the
Peacock comedy-drama series, ''
'Til Jail Do Us Part. She is set to star and produce Volver a caer'', a six-part miniseries that a modern take in Spanish on
Leo Tolstoy's
Anna Karenina. In 2024 she joined the cast of Fox series
The Cleaning Lady. In 2024, del Castillo was cast as Mexican singer
Chavela Vargas in the miniseries
Chavela. She also was cast in the comedy film
The Biggest Fan for Netflix playing the role of disgraced actress Lana Cruz. ==Personal life==