Milburn started a career as a journalist, but then worked freelance for a number of charities including
CAFOD. She also worked as a researcher on a number of
BBC television appeals, including
Challenge Anneka from
Malawi,
Going Live! and
Blue Peter specials from
Jamaica. In 1993 she became the chief executive of the Association of Spinal Injury Research Rehabilitation and Reintegration (ASPIRE) charity for seven years, where she ensured that the Aspire National Training Centre was completed on time and on budget. In July 2000 she became the chief executive of the BBC
Children in Need Appeal, serving until 2004. In May 2004 Milburn became chief executive of
The Prince's Trust, succeeding Sir
Tom Shebbeare who had been at The Prince's Trust for 16 years. Milburn was appointed group chief executive (covering the UK, Australia, Canada, New Zealand, United States and International) in 2017 and retired from the position in 2022. Milburn was a trustee of Media Trust, the UK's leading communications charity, from October 2009 to May 2012. She was appointed Chair of the
Social Mobility Commission in 2018, serving two years until May 2020. As of 2023 she holds active positions at the Windsor Leadership Trust and Dial Global Limited. ==Honours==