Krupsak was a member of the
New York State Assembly from 1969 to 1973, sitting in the
178th and
179th New York State Legislatures. She was initially rebuffed by the state Democratic committee which in June endorsed a then-novice politician,
Mario Cuomo, for the position. Krupsak campaigned through the primary season and won the strong support of women's rights groups, labor unions, and liberal organizations. In the September primary she handily beat both Cuomo and a second rival, liberal Manhattanite
Antonio Olivieri. Contrary to widely reported comments during the campaign, Krupsak was not the first woman nominated by a major New York political party for statewide office. That distinction belongs to
Florence Knapp, a Republican nominated for (and elected to)
New York Secretary of State in 1924. Krupsak, however, was the first woman elected to the lieutenant governorship. Elected with Governor
Hugh Carey, Krupsak became upset with how Carey treated her in office and felt she was not given enough to do. After committing to run for a second term with Carey in
1978, Krupsak decided to withdraw from the ticket and instead challenge Carey for the Democratic nomination for governor. she retired from politics. ==Post-political life==