Botsford graduated from the University of California medical school (now UCSF) in 1896 and trained at the Children's Hospital of San Francisco. She began practicing the following year as one of the country's first physician anesthesiologists. In 1931, she became first faculty anesthesiologist at UCSF. She was the first to use
divinyl oxide as an anesthetic in surgery, during a hysterectomy in January 1932. Throughout her years of practice, she published her research in medical journals on a variety of anesthesia-related topics. She retired from practicing medicine in 1934. During
World War I, she served in the
US Army as a Contract Surgeon of the Medical Corps at Letterman Army Hospital. Botsford is credited with getting a state law passed requiring anesthesia to be taught in medical schools in California. == Personal life ==