Marzuki started his career as an academician, where he first lectured at
International Islamic University of Malaysia in 1999. A close confidant of Muhyiddin Yassin, he started working with him as a research intern at the Center for Leadership and Development Studies (CELDES), whose duties included helping Muhyiddin when he became the Minister of Youth and Sports of Malaysia. He was then appointed as Special Officer to the Deputy Prime Minister of Malaysia when Muhyiddin was appointed as Deputy Prime Minister in 2009. In 2013, he was then promoted as a political secretary to the Minister of Education I of Malaysia. In 2018, he was appointed as the Special Functions Officer to the Minister of Home Affairs until 2020. After the resignation of
Mahathir Mohamad on 24 February 2020, the new Prime Minister, Muhyiddin Yassin took his place and Marzuki was appointed as the Principal Private Secretary, or, in other words, the
Chief of Staff to the Prime Minister of Malaysia. After Tan Sri Muhyiddin resigned as the 8th Prime Minister and was subsequently appointed as the Chairman of the National Rehabilitation Council, Marzuki was appointed as Senior Confidential Secretary to the Chairman of the National Rehabilitation Council. After
GE15, he returned to serve as an associate professor in the Department of Political Science, International Islamic University of Malaysia. ==Personal life==