Masamba is a small river town and district (kecamatan) in the North Luwu Regency of South Sulawesi Province of Indonesia which serves as the seat of the regency. The town lies on the Patikala River. It is served by Andi Jemma Airport. The district covers an area of 1,068.85 km2 and had a population of 38,024 at the 2020 Census; the official estimate as at mid 2023 was 39,266 . Much of the land in the region is swampy coastal plains with mangroves found in its shallow waters.