Yoshida was appointed to manage the Fukushima Daiichi Nuclear Power Plant in June 2010, his fourth stint at Fukushima, just months prior to the
Tohoku earthquake and tsunami on 11 March 2011. After the earthquake struck the plant at 2:46 pm that afternoon, followed by the tsunami at 3:37 pm, Yoshida made the official declaration of nuclear emergency at 4:30 pm. During the early stages of the crisis, the lack of contingency plans and leadership from headquarters gave Yoshida almost complete control and responsibility over the disaster response. Kan later recounted:Yoshida said that this was what we wanted to do, and this was how we were doing it. So, in a very short time he was able to tell me, nicely and clearly what they were doing and why. That was fine with me. If he had gone into details, I wouldn’t have understood it anyway. He managed to convince me that he knew what was going on. On the other hand, Yoshida described Kan as "running amok, yelling and acting in an extremely high-handed manner." Venting work began at 9 am the next morning, shortly after Prime Minister Kan's meeting with Yoshida, but was not completed until 2 pm. The unit suffered a hydrogen explosion less than two hours later which blew off its roof and upper walls. Yoshida is today most remembered for his decision to continue pumping despite the orders from TEPCO management to stop. On 15 March, amid speculation that TEPCO might completely abandon Fukushima and an evacuation of the entire
Kanto region may have become necessary, Yoshida decided to evacuate most of the 650 staff at Fukushima Daiichi to the nearby Daini plant. Yoshida later recounted that at the time of this decision, he had to consider which of his colleagues he would ask to stay behind with him and potentially die in a worst-case scenario. However, around 18 March, after successful cooling and de-pressurization efforts, as well as the expedited delivery of additional fire trucks and an 80-ton
Putzmeister concrete pouring pump truck to the plant, the situation at Fukushima Daiichi stabilized. == Illness and death ==