Route 133 begins at the junction of
Route 38 and
Route 110 in
Lowell, where Route 110 begins a concurrency with Route 38 northbound. Route 133 heads east from this point, heading through the northern end of
Tewksbury, where it has a junction with
I-495 at Exit 94. Shortly after crossing the highway, Route 133 enters
Essex County and the town of
Andover. In Andover, Route 133 crosses
I-93 at Exit 39 and continues eastward, bypassing the town center to the north as it crosses
Route 28 in
Shawsheen Village. From Shawsheen Village, Route 133 heads northward into
North Andover, where the road crosses
Route 114 (the Salem Turnpike) just north of
Merrimack College. It then joins
Route 125 for a concurrency that lasts for . The two routes split next to
Lawrence Municipal Airport, with Route 133 passing the northern banks of
Lake Cochichewick and Route 125 heading northward into
Haverhill. The route passes through the village of West Boxford before continuing into
Georgetown. Center In Georgetown, Route 133 passes south of the Lufkins Brook Area before meeting
Route 97 for a short concurrency that lasts for a tenth of a mile. The two routes split at the center of town, with Route 97 heading northwest on West Main Street and Route 133 heading southeast on East Main Street. Route 133 then crosses
I-95 at Exit 78 before entering the town of
Rowley. In Rowley, Route 133 crosses
U.S Route 1 (the Newburyport Turnpike) at Kent Corner, before it meets
Route 1A. Route 133 then begins a concurrency with Route 1A heading southbound into
Ipswich. In Ipswich, the two routes cross the
Newburyport Line railroad tracks as it enters the downtown area. The two routes cross the historic
Choate Bridge over the
Ipswich River concurrently, before turning southward, passing through the historic village before splitting once more, with Route 133 heading east-southeastward into
Essex. Route 133 passes the northern end of
Route 22 near the crossing of the Essex River before Route 133 heads into
Gloucester. In Gloucester, Route 133 crosses
Route 128 at exit 53 before crossing the Little River (an offshoot of the
Annisquam River) and passing the
West Gloucester MBTA station. Route 133 finally ends at
Route 127, just west of the bridge over the Blynman Canal. ==History==