Market2016 US Open – Men's singles
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2016 US Open – Men's singles

Stan Wawrinka defeated defending champion Novak Djokovic in the final, 6–7(1–7), 6–4, 7–5, 6–3 to win the men's singles tennis title at the 2016 US Open. It was his third major title; on all three occasions, he defeated the world No. 1 player in the final. Wawrinka saved a match point en route to the title, against Dan Evans in the third round. Djokovic was the third man in the Open Era to lose five finals at the same major.

Draw
Finals Top half Section 1 Section 2 Section 3 Section 4 Bottom half Section 5 Section 6 Section 7 Section 8 ==Seeded players==
Seeded players
Seeds are based on the ATP and WTA rankings as of August 22, 2016. Rank and points before are as of August 29, 2016. Withdrawn players The following players would have been seeded, but they withdrew from the event. ==Other entry information==
Other entry information
Wild cards Protected ranking Qualifiers Lucky losers Withdrawals ; Before the tournament ‡ – withdrew from entry list before qualifying began @ – withdrew from entry list after qualifying began § – withdrew from main draw ;During the tournament • Jiří Veselý (left forearm inflammation) ;Retirements ==Notes==
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