The church's history started with the arrival of the Rev John Cox, the first
London Missionary Society missionary in Thiruvananthapuram, in 1838. At this time local Protestants in Thiruvananthapuram worshipped in a church constructed by the Protestant Evangelical Trust in the 1830s. After Rev Cox resigned in 1861, he was succeeded by Rev Samuel Mateer, who led the church for 30 years and died in 1893. By this time the congregation had grown and needed larger premises and it planned to build a new church building in memory of Rev Mateer.
Rev. Samuel Mateer Rev. Samuel Mateer, after whom the church was named, was born near Boardmills in
County Down. He was the first missionary who endeavored to grow an indigenous church. He prepared local people for church ministry and tried to transfer administrative responsibilities to them. It was during his tenure that a number of local people were ordained as ministers. Rev. Mateer is seen as a pioneer of indigenization of the church. When he arrived there were 25 congregations, 3000 Christians and an annual income of Rs. 800/-. However, when he retired after 33 years, the number of congregations had increased to 56, Christians to 10,060 and annual income to Rs. 3000/-. He wrote two books about his time in Travancore,
Native Life in Travancore and
The Land of Charity. In 1890, Mrs. Mateer had to return to England owing to ill health. Rev. Samuel Mateer went to England in 1891 on leave, and died there on 24 December 1893. He is buried at Clifton Street Cemetery in Belfast. It was in the same year that the Thiruvananthapuram Church was promoted to the position of a pastorate. The church building constructed in the LMS compound and dedicated to the memory of Mateer was opened for worship on 1 December 1906. ==Later history==