Wolverhampton Wanderers Doherty was spotted by
Wolverhampton Wanderers while playing for
Bohemians in a pre-season game against them in July 2010. Despite never having played a first team game for Bohemians, he was invited for a trial and soon signed a two-year deal (with the option of a further year) to move to the English club for a reported £75,000 fee. The defender made his Wolves debut on 8 January 2011 in an
FA Cup tie against
Doncaster Rovers, before making his Premier League debut on 24 September 2011 at
Liverpool. In January 2012, Doherty was loaned to
Scottish Premier League club
Hibernian for the latter part of the 2011–12 season. Here, he played in every
defensive position, although his preference was right-back. After making his debut in a 1–0 victory against
Kilmarnock on 4 February in the
Scottish Cup, he went on to make a total of 17 appearances for the club, in which he scored twice. His final game of the loan spell was the
2012 Scottish Cup final, against
Edinburgh derby rivals
Hearts, where Hibs lost 1–5. Doherty later apologised for the team's performance. In October 2012, Doherty was again loaned out, joining
League One club
Bury in a three-month deal. Two days later, Doherty made his debut for Bury, in a 0–1 defeat to
Swindon Town, in the first of 22 appearances for the club. He established himself in the first team, playing in the right-back position and earning praise from manager
Kevin Blackwell. However financial troubles at Bury meant that their loan players, such as Doherty, were sent back to their parent clubs in January 2013. With
Dean Saunders appointed Wolves manager in January 2013, Doherty was soon promoted to becoming the club's regular right-back and he featured throughout the final months of the 2012–13 season as the team battled unsuccessfully to avoid a second consecutive relegation. Under Saunders' successor,
Kenny Jackett, Doherty retained his place in the Wolves' team and, in September 2013, signed a new contract. Doherty's goal against Fulham at
Molineux during the 2015–16 campaign was awarded the club's best goal of the season. On 26 September 2017, he signed a new contract keeping him at Wolves until the summer of 2021. Towards the end of the 2017–18 campaign, Wolves were promoted back to the
Premier League after a six-year absence. Doherty scored his first Premier League goal for Wolves (on his ninth appearance in the Premier League) on 6 October 2018 at
Crystal Palace as the team won 1–0. Two days later it was announced that Doherty had won the
Professional Footballers' Association Fans' Premier League Player of the Month award for September 2018, becoming only the fourth Ireland player to win this award in the history of the Premier League. Doherty scored his second Premier League goal for Wolves on his 200th league appearance for the club on 30 November 2018 at
Cardiff City in a 2–1 defeat. The following 15 February, he signed a new contract that would keep him at the club until the summer of 2023. Doherty scored his fourth Premier League goal, and his first Premier League goal to be scored at Molineux, in a 3–1 win over
Arsenal, Wolves's first win against Arsenal since 1979, on 24 April 2019. That 8 August, he scored the team's first goal in a 4–0 win on his debut appearance in European competition in the
UEFA Europa League Qualifying Third Round, 1st Leg, against
FC Pyunik in
Yerevan,
Armenia. Writing in
The Guardian in December 2019, Paul Doyle declared Doherty Wolves' best player of the decade. He marked his 300th appearance for the club (in all competitions) in their last league game of the
2019–20 season away to
Chelsea on 26 July 2020. The 302nd and final appearance of his ten-year spell, was in the 2019–20 UEFA Europa League quarter-final against
Sevilla on 11 August.
Tottenham Hotspur On 30 August 2020, Doherty was sold to
Tottenham Hotspur for £13.4 million with no add-ons and signed on a four-year deal. As a life-long
Arsenal fan, Doherty had expressed his love of Tottenham's local rivals on social media, and on signing for Tottenham the player and club made a light-hearted video about the deletion of these historic comments. He made his debut on 13 September in a 1–0 home defeat against
Everton. Doherty battled for his right-back place against
Serge Aurier. On 2 January 2021, he was sent off at the end of a 3–0 home win over
Leeds United. On 26 February 2022, Doherty scored his first goal for Tottenham in a Premier League clash against Leeds United at
Elland Road. Tottenham eventually won the game 4–0 in which
Son Heung-min and
Harry Kane also became the Premier League's deadliest partnership in terms of goals and assists for each other. On 9 April 2022, Doherty suffered a
medial collateral ligament injury in a win over
Aston Villa that kept him out of action for the rest of the season. Doherty scored his first goal of the 2022–23 season – his third for the club – in Spurs' 4–0 win over
Crystal Palace at
Selhurst Park on 4 January 2023.
Atlético Madrid On 31 January 2023, Spurs terminated Doherty's contract so he could join
La Liga club
Atlético Madrid. He featured just twice for Atlético, and left the club as a free agent.
Return to Wolves On 20 July 2023, Doherty returned to
Wolverhampton Wanderers on a three-year contract on a free transfer. Doherty returned to first-team action for Wolves, three years and 18 days after last featuring for the club, in a home
EFL Cup game against
Blackpool on 29 August 2023, and announced his return with a brace of goals in a 5–0 win. Doherty scored his first Wolves goal in the Premier League since returning to the club in the close season on Christmas Eve 2023 at Molineux, the first 24 December league fixture in 28 years: the winner in a 2–1 victory over
Chelsea. ==International career==