Backstory Karen Simonds was born in 1943. She has two sisters: Gale and Roberta (
Lily Tomlin). She worked as a model of corsets for
Sears Roebuck through college. In 1963 she became the second wife of Gilbert McCluskey (
John Harnagel) and they moved into Fairview, 4358 Wisteria Lane in 1982. They had a child who died when he was 12 years old, for an unknown reason.
Season 1 Karen McCluskey becomes the neighborhood nemesis of
Lynette Scavo, until Lynette helps her when she collapses, leading them to become friends.
Season 2 On one occasion, Karen accidentally
tasers Lynette's co-worker Stu when she believes he was trying to abduct Lynette's kids. She is also one of the first to become aware of
Danielle Van de Kamp's relationship with
Matthew Applewhite. Later, she finds Bree passed out on the front lawn after drinking heavily. She subsequently alerts Lynette that Bree had been drinking while babysitting her kids. Afterwards, she frequently babysits the Scavo kids and eventually supports Lynette's decision to follow Tom to Atlantic City when she suspects infidelity.
Season 3 Karen becomes closer to her neighbors and is often seen gathering with
Lynette Scavo,
Gabrielle Solis and
Susan Mayer. After Karen breaks her arm and is in the hospital, first
Parker Scavo, then
Ida Greenberg discover the dead body of Gilbert, her husband, in her freezer. Ida goes to the police, and Karen is briefly jailed for improper disposal of a body. Karen becomes the subject of rumormongering as a result. While enduring harassment from her neighbors, Parker continues to defend her and tells Karen to just tell the truth to stop the rumors. After some time, Karen decides to come clean to the neighborhood and explains that after her husband's death, she realized Gilbert had neglected to update his pension files, accidentally leaving all of his assets to his first wife. Karen kept his body in a freezer in her basement for the next 10 years so she could continue cashing his pension checks. The neighborhood accepts her again, and Lynette hires her back as their babysitter.
Season 4 When a
tornado hits Wisteria Lane, Karen reluctantly invites the Scavo's to take shelter in her house, along with herself, Ida and Ida's cat Toby. Karen refuses to evict Toby when Lynette argues that Tom is allergic to cats, and she catches Lynette trying to smuggle Toby from the basement. During the argument, the door blows open and Toby escapes. As Karen tries to get Toby back into her house, Lynette catches her. They try to get back into the house, but when things block their way, they take refuge in Lynette's bathtub. After the tornado passes, they step outside, only to find Mrs. McCluskey's house in ruins. Although Tom and the Scavo kids miraculously survive, Ida is killed. Toby also survives and is adopted by Karen. As Lynette and Karen pack Ida's belongings, they think of spreading the ashes at a baseball stadium where Ida used to play, but Ida's niece and nephew want to take the urn back to Omaha, Nebraska. Karen and Lynette then switch Ida's ashes for dust from a vacuum cleaner, and later break into the baseball stadium and spread Ida's ashes around the field.
Season 5 After the five-year leap for the fifth season, when Edie returns to Fairview with her new husband,
Dave Williams (
Neal McDonough), Karen welcomes her back and teases her like they used to do. When Edie gets upset, Dave asks Karen to stop, but she refuses. As retaliation, Dave abducts her cat Toby and refuses to return him until she apologizes to Edie. Karen's suspicions of Dave grow, and she begins to investigate him. After Dave breaks into Karen's house and moves things around in order to feign her
dementia, she tries to attack him with a bat at her 70th birthday party. She is stopped and taken away in an ambulance. In the hospital, Karen apologizes to Edie, claiming her pills had made her attack Dave. However, she asks her sister Roberta to come to town, and they continue to investigate him. Later, after Edie dies in a car accident, Karen, along with Susan, Gabrielle, Bree and Lynette, are asked by Dave to take her ashes to her son Travers. Travers declines keeping the ashes, leaving Karen to figure out what to do with the ashes. She decides to spread Edie's ashes through the neighborhood, with the help of the other housewives.
Season 6 After Karen watches Julie Mayer fight with Danny Bolen, Julie is attacked by an unknown assailant and ends up in a coma. Karen is initially hesitant to tell the police about the altercation between Julie and Danny. Her boyfriend, Roy Bender, convinces her to go through with it, rationalizing that she doesn't have to do it alone, and using this as an opportunity to confess his love for her. Karen later watches as Danny is brought in for questioning. Later, Karen visits Katherine at the mental hospital she is staying at, to encourage her to come back to Wisteria Lane. She later brings the housewives with her to convince her to come back. After Karen becomes engaged to Roy, she learns she has lung cancer. However, two episodes later in "
My Two Young Men" we learn that Karen has already beaten cancer, and Roy throws a party for her, which all the neighbors of Wisteria Lane attend.
Season 7 Karen alerts the women of
Paul Young's return in the first episode "
Remember Paul?", and she later tells Paul's wife
Beth about
Martha Huber and that everybody believed Paul had killed her. Roy returns in "
A Humiliating Business" where it is revealed that he and Karen have now married. She later then lets Porter and Preston live at her house when Lynette tells them to find a place of their own, however their time is short lived as Karen kicks them out after they have a house party. After her prison release
Felicia Tilman moves next door to Karen, and they talk and reveal that Karen witnessed Felicia faking her death and kept her secret.
Season 8 Karen is once again diagnosed with terminal lung cancer. In the series finale, Karen is preparing to head to a hospice, but the women of the Lane insist on taking care of her themselves. After she overhears Gabrielle and Carlos talking about
Carlos killing Gabby's stepfather, Karen goes on the stand at Bree's murder trial and falsely confesses to killing Alejandro herself, using details she had overheard to convince the jury. While doubtful of Karen's story, the district attorney throws the case out, and no charges are pressed against Karen due to her age and illness. Karen dies at home, listening to the song "
Wonderful! Wonderful!" sung by Johnny Mathis. Then her spirit is seen joining those who have died over the years on Wisteria Lane. She is seen in the final scene of the show reunited with her son. ==Behind the scenes==