Defensor Born in
Rivera, Lemos was a
Defensor Sporting youth graduate. On 6 January 2014, aged 18, he was promoted to the main squad. Lemos made his professional debut on 11 May 2014, starting in a 2–1 home loss against
Montevideo Wanderers. After appearing in only two matches during
his debut campaign, he was more regularly used in
his second; however, his appearances were limited due to an
appendicitis and call-ups to the
under-20 national team.
Rubin Kazan On 3 July 2015, Lemos was loaned to
Russian Premier League side
FC Rubin Kazan, for one year. He made his debut for the club on 3 August, playing the full 90 minutes in a 1–0 away defeat to
Spartak Moscow. After appearing in eight matches for the club (four in the league), Lemos was bought outright.
Las Palmas On 28 January 2016, Lemos was loaned to
La Liga side
UD Las Palmas, with a buyout clause. He made his debut in the competition on 20 February, coming on as a second-half
substitute for
Jonathan Viera in a 1–2 home loss against
FC Barcelona. On 6 May 2016, after appearing in nine matches for the
Amarillos, Lemos signed a permanent five-year deal with the club effective in July. He scored his first goal in the main category of Spanish football the following 30 January, netting his team's second in a 3–1 home win against
Valencia CF. On 10 March 2017, Lemos scored a brace in a 4–3 away win against
RCD Espanyol.
Sassuolo (loan) On 22 January 2018, Las Palmas announced they had reached an agreement with Italian club
Sassuolo for the loan of Lemos.
Fenerbahçe On 26 August 2020,
Fenerbahçe announced the signing of Lemos on a three-year contract.
Beerschot (loan) On 31 August 2021, Lemos was loaned to Belgian club
K Beerschot VA for the
2021–22 season.
Atlético Mineiro On 16 February 2023, Lemos joined Brazilian club
Atlético Mineiro on a ten-month deal.
Vasco da Gama On 15 January 2025, Lemos signed a one-year deal with
Vasco da Gama.
Peñarol He signed for Urugyuan club
Peñarol in February 2026, something he described as a dream. He told the club that "you'll have a fan on the pitch". ==International career==