Study of fatigue Having been trained in experimental methods by
McDougall, Smith developed and carried out a major study on the effects of fatigue. Using herself as the sole research subject, she restricted herself to only 1.5, 3.5 and 5.5 hours of sleep on successive nights, using a variety of tests to evaluate the consequences. These included serial word recall, the capacity to learn nonsense syllables, and performance on several physical tasks. She carried on the experiment for three years, averaging five days a week. She found that there was a brief period immediately after the initial sleep deprivation in which the subject's performance was improved, but that this was followed by a long period in which performance was diminished, and that recovery was slow. She also noted that the fatigued subject's ability to judge her own effectiveness was impaired, "extremely bad work being not infrequently accompanied by a conviction that it is unusually good".
Effects of alcohol and opium on efficiency Among other research projects, Smith worked with McDougall on studying the effects of alcohol and opium on efficiency. This experience led to her being hired to interview incarcerated prostitutes to determine whether or not "drink had contributed largely to their choice of occupation", a hypothesis that was not supported by her findings.
Telegraphist's cramp One of her most important contributions began with a study, in collaboration with Culpin and Eric Farmer, of a condition called "telegraphist's cramp", a type of
focal dystonia of the hand which had been thought to be caused by physical fatigue. It was the basis for further research by Smith and Culpin into psychological factors in other occupational diseases, resulting in 1930 in a "landmark" report entitled
The Nervous Temperament. This work was notable both for its results and for its experimental design, which combined interview-based clinical assessments and objective tests. Demonstrating a positive correlation between Culpin's clinical assessments and Smith's test results, the study provided evidence that psychoneurosis is one of the factors responsible for industrial illness. Moreover, it enhanced the legitimacy of
clinical psychology, which was a relatively new discipline. ==Career==