At the center of Mazatec healing practices is the ritual ingestion of Psilocybe mushrooms, known locally as
ndi xijtho ("the little ones that sprout") or “holy children.” These mushrooms are not merely seen as substances, but as conscious entities capable of communicating wisdom and healing. Their use occurs during nocturnal ceremonies known as veladas, which involve prayer, chanting, incense, and symbolic offerings. Mazatec
veladas ceremonies are highly structured nighttime rituals guided by a shaman or
chjota chijne. These rituals are often conducted in dark, quiet environments, often within the shaman’s home or a designated ceremonial space. The use of candles, incense, flowers, and Catholic imagery is a direct parallel to the "Set, Setting, and Dose" concept in modern psychedelic medicine. When mushrooms are not in season, Mazatec shamans may instead use other visionary plants such as Salvia divinorum (Ska Pastora), or seeds from Rivea corymbosa and
Ipomoea violacea, commonly called “Seeds of the Virgin.” Each plant is selected based on the shaman’s specialization, the season, and the patient’s needs. The ritual use of these plants often facilitates an ecstatic trance through which the shaman may diagnose illness, find lost objects or souls, and seek spiritual guidance. Participants in
velada ceremonies fast and abstain from sexual activity prior to the ceremony. The shaman leads the ritual through chanting and invocation, using poetic and metaphorical language referred to as the "language of the saints." These chants are considered central to the healing process and are believed to guide both the participants and the spiritual forces involved. == Training and selection ==