Medscape launched May 22, 1995, by SCP Communications, Inc. under the direction of its CEO Peter Frishauf. The first editor of Medscape was a P.A. named Stephen Smith. In 1999,
George D. Lundberg became the editor-in-chief of Medscape. For seventeen years before joining Medscape he served as editor of the
Journal of the American Medical Association. In September 1999, Medscape, Inc. went public and began trading on
NASDAQ under the symbol MSCP. In 2000, Medscape merged with MedicaLogic, Inc., another public company. MedicaLogic filed for bankruptcy within 18 months and sold Medscape to
WebMD in December 2001. In 2008, Lundberg was terminated by WebMD. The following year the
Medscape Journal of Medicine ceased publishing. In January 2013,
Eric Topol was named editor-in-chief of Medscape. The same year, Lundberg returned to Medscape as
editor-at-large. In 2009, WebMD released an iOS application of Medscape, followed by an Android version two years later. In 2015, WebMD launched Medscape CME & Education on iOS. In 2021, Medscape launched Medscape UK to expand their business in United Kingdom. In November 2025, Medscape launched Medscape AI, a generative artificial intelligence tool designed for clinicians. The platform integrates Medscape’s proprietary content with peer-reviewed literature from more than 400 medical journals, as well as real-time medical news. According to Medscape, the tool is designed to exclude unverified information from the open internet and provides cited AI responses with regular human editorial oversight, providing transparent and reliable responses. Medscape AI was developed with input from clinicians and is available to registered Medscape users at no cost. ==Criticisms==