Debut and early success (2016-2017) Pirzada made her acting debut with the 2016 Telugu film
Krishna Gaadi Veera Prema Gaadha, in which she played Mahalakshmi opposite
Nani. The film was a major box office success. A reviewer of
Sify stated that she came up with "decent performance" in her first film. Pirzada had five releases in 2017. She played Anu in her Hindi film
Phillauri opposite
Suraj Sharma. The film received mixed reviews and was a commercial failure. Andy Webster of
The New York Times stated that she brings the "spark". Next, she played Meghana in
Mahanubhavudu opposite
Sharwanand. Hemanth Kumar of
Firstpost said, "Mehreen makes quite an impression." Pirzada then played Lucky opposite
Ravi Teja, a major success at box office. After this, she appeared as Janani in the bilingual
Nenjil Thunivirundhal, opposite
Sundeep Kishan. Lastly, she played Bhargavi opposite
Sai Dharam Tej in
Jawaan, a commercial failure.
Career expansion (2018-2020) In 2018, Pirzada first played Akshara opposite
Gopichand in
Pantham. Next, she appeared opposite
Vijay Deverakonda in
NOTA as Swati. She then played Lavanya opposite
Bellamkonda Sreenivas in
Kavacham. All the three films were commercial failures. In her first film of 2019, Pirzada played a dominating wife Honey, opposite
Varun Tej, in
F2: Fun and Frustration. It was a huge commercial success. Krishna Sripaada from
The News Minute stated, "While accents are a huge problem, the leading ladies, are funny, especially Mehreen, who gets a lot of mileage out of her role." Next, she made her Punjabi debut with
DSP Dev, playing Kirat opposite
Dev Kharoud. She reunited with Gopichand in
Chanakya, playing Aishwarya. In the same year, she played Shruti opposite
Ninja in
Ardab Mutiyaran. Manpriya Singh of
The Tribune said that she plays her role "remarkably well". In 2020, Pirzada played Nandhini opposite
Nandamuri Kalyan Ram in
Entha Manchivaadavuraa. Then, she appeared as Sadhana opposite
Dhanush in
Pattas, which became a commercial success.
The Times of India found her performance to be "lifeless". Her last film of the year saw her playing Neha, opposite
Naga Shaurya in
Aswathama.
123Telugu wrote "Mehreen doesn’t get much scope to stamp her identity in this film, though she looks at ease in the songs."
Fluctuation and recent work (2021-present) In her only film of 2021, Pirzada appeared as Padma in
Manchi Rojulochaie opposite
Santosh Sobhan. Writing for
The New Indian Express, Murali Krishna Ch stated, "Mehreen fails to impress and her expressions are not in sync with the dubbing." In 2022, Pirzada reprised Honey in
F3: Fun and Frustration, reuniting with Varun Tej. It emerged as one of the year's highest grossing film. In 2023, Pirzada made her web debut with
Sultan of Delhi, playing Sanjana opposite
Tahir Raj Bhasin. Later, she played Lekha in
Spark L.I.F.E., opposite Vikrant Reddy.
123telugu noted, "Mehreen looked good and performed well according to her role." == Personal life ==