Early career After he suffered a submission loss in his MMA debut in 2014, Melsik would wait until 2019 for his second MMA bout. Baghdasaryan amassed a four fight knockout winning streak, with a cumulative fight time of 62 seconds. In the last of those four fights, against Art Hernandez, he made his lightweight debut. Baghdasaryan was given a chance to fight for a
UFC contract at
Dana White's Contender Series 31, when he faced Dennis Buzukja. He won the fight by a unanimous decision, but was not given a contract.
Ultimate Fighting Championship In March 2021, Baghdasaryan signed with the UFC. Baghdasaryan made his promotional debut against Collin Anglin at
UFC on ESPN 28 on July 31, 2021. He won the fight via knockout in round two. This fight earned him the
Performance of the Night award. Baghdasaryan was scheduled to face T.J. Laramie November 6, 2021 at
UFC 268. However, Laramie was forced to pull out due to diagnosed with
MRSA. He was replaced by
LFA Featherweight Champion Bruno Souza in his promotional debut. At the weigh-ins, Souza weighed in at 148.4 pounds, 2.4 pounds over the featherweight non-title fight limit. The bout proceeded at a catchweight and he forfeited 20% of his purse to Baghdasaryan. He won the bout via unanimous decision. Baghdasaryan was scheduled to face T.J. Laramie on April 16, 2022, at
UFC Fight Night 206. However, Melsik pulled out for unknown reasons. Baghdasaryan was expected to face Joanderson Brito on October 15, 2022, at
UFC Fight Night 212. However, Baghdasaryan pulled out in late September due to a broken hand. Baghdasaryan faced
Joshua Culibao on February 12, 2023, at
UFC 284. He lost the fight via a rear-naked choke submission in the second round. Baghdasaryan next faced Tucker Lutz at
UFC on ESPN 49 on July 15, 2023, winning the bout via unanimous decision. Baghdasaryan was scheduled to face William Gomis on February 3, 2024,
UFC Fight Night 235. However, Gomis pulled out due to undisclosed reasons in early January. Baghdasaryan was eventually rebooked a week later against Hyder Amil on February 10, 2024, at
UFC Fight Night 236, replacing
Shayilan Nuerdanbieke. In turn, Baghdasaryan pulled out on fight week due to injury and was replaced by Fernie Garcia. Baghdasaryan was scheduled to face
Muhammad Naimov on June 22, 2024 at
UFC on ABC 6. However, Baghdasaryan pulled out during fight week due to a torn labrum in his left shoulder. Baghdasaryan faced
Jean Silva on February 22, 2025 at
UFC Fight Night 252. He lost the fight by technical knockout in the first round. Baghdasaryan was scheduled to face Joanderson Brito on December 13, 2025, at
UFC on ESPN 73. However, Baghdasaryan withdrew from the bout for undisclosed reasons and was replaced by promotional newcomer Isaac Thomson. Baghdasaryan is scheduled to face promotional newcomer Murtazali Magomedov on June 20, 2026 at
UFC Fight Night 279. ==Championships and accomplishments==