Original Orlando production The original Orlando production opened on March 28, 2001, at the Church Street Theatre building, that was specifically converted from a perfume shop into a 76-seat theatre for the show. Its original cast members were Shelly Browne as the Power Woman (later renamed the Professional Woman), Patti McGuire as the Iowa Housewife, Pammie O'Bannon as the Earth Mother, and Wesley Williams as the Soap Star. The show then transferred to
West Palm Beach's Cuillo Center on June 22, 2001.
Original off-Broadway productions The
Off-Broadway production officially opened at Theatre Four on April 4, 2002, after a month of previews. It then transferred to Playhouse 91 in September of that year. After running for four years, the Off-Broadway production closed in May 2006.
North American productions in Reno, Nevada in 2009. Alongside the New York and Florida runs, GFour Productions mounted further sit-down productions throughout the United States. These opened at the
Apollo Theatre in
Chicago on July 25, 2003, becoming the highest grossing musical in the theatre's history after 1,281 performances, the
Coronet Theatre in
Los Angeles on October 30, 2003, the
Gem Theatre in
Detroit on March 17, 2004, becoming the longest running show in Michigan's history and the Stuart Street Playhouse in
Boston on March 31, 2004, running for 1,092 performances. Since 2006 American actress
Ingrid Cole is a member of Menopause the Musical. The Las Vegas production has been running continuously since 2006, currently at
Harrah's Las Vegas. This was followed by a national tour that continues to run as of November 2021, reaching over 500 cities worldwide. A further American tour specifically to raise funds and awareness for the fight against
ovarian cancer was later launched in 2015.
International productions International productions have been staged all over the world. Local references in the show are customized to the location of the performance. For example, the '
Iowa Housewife' became '
Dubbo Housewife' in Australia; America's Bloomingdale's became
Marks & Spencer in London. ==Original US production musical numbers==