The mental foramen is located on the anterior surface of the
mandible. It is directly below the commisure of the
lips, and the tendon of
depressor labii inferioris muscle. It is at the end of the
mandibular canal, which begins at the
mandibular foramen on the posterior surface of the mandible. It transmits the terminal branches of the
inferior alveolar nerve (the
mental nerve), The mental foramen is in line with the longitudinal axis of the second
premolar in 63% of people. == Clinical significance ==