Service at this station began on 20 November 1970, when
Line 1 was expanded westwards from
Juanacatlán to Tacubaya. On 22 August 1985, Metro Tacubaya became a transfer station, when the second stretch of
Line 7 was inaugurated, from
Auditorio to Tacubaya. In 1988,
Line 9 was connected to the station as part of the final stretch of Line 9, inaugurated on 29 August 1988, going from
Centro Médico to Tacubaya, thus becoming the western terminus of the line. According to earlier plans for the metro, Line 9 was supposed to be extended towards
Observatorio. This is the reason why on Line 9 platforms of Tacubaya signs stating that the station is a provisional terminal can be seen since its opening in 1988. In 2018, the
Sistema de Transporte Colectivo announced plans to complete this expansion from Tacubaya to Observatorio. Mexico City government announced shortly after that no works would be done during 2019; and as of early 2020, works still have not been started.
March 2020 train crash On March 10, 2020, at about 23:37 local time (05:37 GMT), two trains crashed while both were going towards
Observatorio station. The first train, No. 38, was parked at Tacubaya's platform when it was hit by another train, No. 33, that came in reverse at . According to official reports, 1 person died and 41 were injured, all inside train No. 33; people in train No. 38 were evacuated moments before the crash. Authorities from the Sistema Transporte Colectivo Metro believe the crash was caused due to a failure in the train systems coupled with a 7-degree slope that propelled train No. 33 for a kilometer (0.62 mi), that occurred after performing a parking maneuver at Observatorio station.
2024 stabbing attack On 19 November 2024, a man stabbed four people at the Line 7 platforms. The attacker was arrested. ==General information==