It is a large building, with a high gabled roof. It has two plastered towers, once painted red on top, inlaid with
mother-of-pearl that were considered the tallest in Panama for a long time. The walls are made of stone, the façade is carved in the
Renaissance style with classical elements of decoration (usually called
Jesuit style). It has three naves that are directly accessed through three doors from the façade. There are two other chapel naves that are missing the respective divisions. The roof is supported by a veritable forest of about 67 cruciform columns made of stone and brick. The sanctuary and the Christ statue are seven steps above the level of the naves and although everything is painted white, that section, at the top, is painted in light blue, colors of the Virgin. Its main altarpiece is a work from the end of the 19th century, very possibly made by French masters who worked for the construction of the Interoceanic Canal. From Darién to Panamá Viejo and from there to the current site, came the relics brought from
Seville of
Saint Aurelio of Córdoba and
Saint Getulius, in both cases, complete remains. The bells of the cathedral tower of
Panama Viejo were rendered useless when they partially melted in the fire of 1737, so the bells that it now bears were made in the eighteenth century, as gifts from former Panamanian bishops who had been transferred to South America. It has a wide
sacristy, once on two levels, the only Panamanian colonial building with a
dome. Under the sanctuary-most holy there are two vaulted rooms, the Crypt of the Bishops. From the sacristy it was possible to access another lower room where the archives of the cathedral rested. It has 10 large and tall windows that have been enriched since the beginning of the twentieth century with beautiful stained glass windows influenced by ''l'art decorative''. The current lamps, made of gilded bronze with a traditional design, were donated by the
Archdiocese of Rio de Janeiro. The cathedral stands on the west side of the Plaza Mayor. It is surrounded by a wide hillock 6 steps above street level and one more step to enter the temple. == Elevated to Basilica==