In 1981, Barber was appointed to the electrical engineering team at General Electric. He started his career working on software for
X-ray imaging systems. After eight years, he moved to
computer tomography, where he developed firmware and hardware, and eventually to
magnetic resonance imaging. Barber established Healthymagination, the GE strategy on global health, where he was responsible for reducing the costs associated with accessing care by more than 15%. Barber was made Chief Technology Officer of General Electric Healthcare in 2007, chief operating officer in 2013, and President of
computer tomography. He retired from his engineering role in 2020, and was made Chief Diversity Officer. At General Electric, Barber developed the Human Resources program, including their African American forum. He serves on the Board of the National Action Council for Minorities in Engineering. He joined the board of
Catalent in 2021. == Awards and honors ==