After earning his Ph.D., Roukes spent seven years as a member of the technical staff and principal investigator in the Quantum Structures Research group at Bell Communications Research in New Jersey, focusing on
mesoscopic physics of electron transport in nanostructures. Roukes left Bellcore to become a tenured associate professor of physics at Caltech in 1992, rising to full professorship in 1995, and subsequently became professor of physics, applied physics, and bioengineering in 2000. Upon moving to Caltech, his principal research focus changed to
nanoelectromechanical systems (NEMS). As the earliest pioneer in this field,
DARPA engaged Roukes to organize the first international workshop on NEMS in 1999, followed by a large international conference and school on nanoscale and molecular mechanics in 2002. The many alumni from his group continue to advance this field at major universities in the U.S. and abroad. Roukes' other research efforts at Caltech have focused on thermal properties of
nanostructures, semiconductor
spintronics, and, more recently,
nanobiotechnology. In 2002, Roukes was named the founding director of the
Kavli Nanoscience Institute (KNI) at Caltech. After stepping down between 2006 and 2008, to focus on co-founding the international
Alliance for Nanosystems VLSI (huge scale integration) and to pursue collaborative research on NEMS VLSI in connection with a ''Chaire d'Excellence'' in Nanoscience in Grenoble (with scientists at
CEA/
LETI-
Minatec), Roukes returned as co-director of the KNI in 2008. Roukes was named a recipient of the
National Institutes of Health Director's Pioneer Award in 2010. In 2012, he was named Chevalier (Knight) of the
Ordre des Palmes Académiques by the Republic of France. Among his groups' principal achievements at Bell were observation of quenching of the Hall effect in a quasi-one-dimensional wire, elucidation of electron-boundary scattering in quantum wires, invention of "anti"-dots and elucidation of commensurability effects in this system, first elucidation of chaotic transport in mesoscopic conductor, and direct measurement of the transmission matrix for a mesoscopic conductor. Among his groups' principal achievements at Caltech are development of the first nanoelectromechanical systems, measurement of the
quantum of thermal conductance, first attainment of attogram mass resolution with a NEMS resonator, first measurement of nanodevice motion at microwave frequencies, discovery of the giant planar Hall effect in semiconducting ferromagnets, observation and control of a single domain wall in a ferromagnetic semiconducting wire, first demonstration of zeptogram-scale mass sensing, first coupling of a qubit to a NEMS resonator, and first demonstration of nanomechanical mass spectrometry of single protein molecules. Roukes has authored or co-authored highly cited general interest articles on nanophysics, nanoelectromechanical systems, spintronics, and quantum electromechanics. Roukes and his collaborators have been issued 57 patents in their fields of research. An electron micrograph of the quantum of thermal conductance device, taken by postdoc
Keith Schwab and colorized by Roukes, was acquired for the permanent collection of the
Museum of Modern Art in 2008. ==Events, affiliations and campaigning==