O' Higgins is an Irish surname and a sept of the O' Neill family. It may refer to:Bernard O' Higgins, Bishop of Elphin (1542–64) William T. O' Higgins, Irish-American, Catholic chaplain during the American Civil War the following Irish politicians : Kevin O' Higgins, Irish politician Thomas F. O' Higgins, Irish politician Tom O'Higgins, Irish politician, barrister, and judge Michael O' Higgins, Irish politician the following Chilean politicians : Bernardo O' Higgins, Chilean independence leader Ambrosio O'Higgins, 1st Marquess of Osorno, colonial governor of Spanish America; father of Bernardo