Different types of microcoils with different fabrication techniques are employed for NMR:
Solenoid microcoils Is the classical geometry to create a
magnetic field with an
electric current. Even for a limited number of windings this geometry provides a reasonable homogeneous B1 field and a good filling factor is possible by winding the coil directly onto a holder containing the sample. Miniaturization to a scale of several hundred micrometers (μm) is not very difficult although the wire diameter (typically 20 to 50 μm) becomes very small and a freestanding coil is a very delicate object. A reduction to below 100 μm diameter is possible but the machining and handling of such coils will be rather tedious. For this reason other microsystem fabrication technology such as
bulk micromachining,
LIGA and
micro-injection molding should be applied. For solenoid coils adding more turns to the coil will enhance the B1/i ratio and thus both the inductance and the signal response. At the same time the coil resistance will increase linearly, so the improvement in sensitivity will be proportional to the square root of the number of turns (n). At the same time we will have a larger
ohmic heating at the center of the coil and an enhanced danger for arcing, so the optimum is generally found for only a limited number of turns. Besides RF performance, static field distortions due to susceptibility effects are an important factor in the design of microcoil probeheads.
Planar microcoils Is the most common geometry used, based on a spiral design with the center winding contacted to the outside using a connection to another layer which is electrically isolated with a thin oxide layer. In this configuration the axis of the RF coil will be oriented perpendicular to the external static field B0.
Saddle microcoils The saddle coil shows the most complex geometry of these three coil types. The B1 field is generated primarily by the four vertical wire segments. Because of this coil geometry, the B1 field of a saddle coil is more homogeneous in z direction than that of a planar coil. The saddle coil can be formed from wire, but it is also often etched from thin copper foil, which is then adhered to glass or PTFE tubing. The latter procedure leads to a high geometric precision, resulting in better B1 homogeneity. The saddle coil is easily accessible and provides a good 'filling factor' of the usable area in the magnet bore. For these reasons it is widely used in NMR microscopy. However, these advantages are achieved at the price of decreased sensitivity. Compared to a saddle coil, the sensitivity performance of a solenoidal coil of the same dimensions is approximately three times better.
Self-assembled microcoils Self-assembled rolled-up micro coils with diameters down to 50 μm have been developed for NMR microscopy. == References ==