After Germany invaded the Soviet Union, Khozin was dispatched to hold an operational post in July, becoming deputy commander for the rear of
Georgy Zhukov's
Front of Reserve Armies. He was made a deputy chief of the General Staff on 4 September, responsible for the Leningrad axis. When Zhukov took command of the
Leningrad Front, he brought Khozin with him as his chief of staff on 13 September. Khozin simultaneously commanded the
54th Army from 26 September during operations aiming to break the
Siege of Leningrad in the region of
Kolpino. After Zhukov departed the Leningrad Front Khozin succeeded him in command on 27 October. Khozin led the front during the
Tikhvin defensive and offensive operations, and in April 1942 took simultaneous command of the
Volkhov Group of Forces, reduced in status from the previously independent Volkhov Front. For his failure to relieve the
2nd Shock Army, Khozin was relieved of command in June and appointed commander of the
33rd Army, fighting on the
Vyazma axis. He served as deputy commander of the
Western Front between October and December. Zhukov selected Khozin to lead the
20th Army on 7 December, replacing the dismissed
Nikolay Kiryukhin as the army prepared for
Operation Mars. Khozin's army was tasked with attacking the German defenses on the
Vazuza river bridgehead, and due to the understrength, demoralized and inexperienced conditions of his units Khozin's plan for the offensive relied on a frontal attack. The army suffered heavy losses in a series of costly attacks and the offensive culminated by mid-December. Khozin was replaced in command of the army and appointed Stavka representative to the
3rd Tank Army, serving in this capacity during the
Ostrogozhsk–Rossosh offensive. In January 1943 Khozin was promoted to the rank of
general-polkovnik. Khozin commanded the Special Group of Forces created to eliminate the German Demyansk salient in the
Demyansk Offensive between February and March. Khozin's group reported directly to
Stavka and operated in the zone of the
Northwestern Front. Khozin became deputy commander of the Northwestern Front in April, and transferred to hold the same position for the Western Front. He was dismissed from this position by a Stavka order on 8 December for inactivity and an unserious attitude to his duties. In March 1944 he was appointed commander of the
Volga Military District in the rear, remaining in this post for the rest of the war. == Postwar ==