State Highway 50 was authorized in 1920 between
Cannon Falls and
Minneapolis.
U.S. Highway 55 was routed along this highway in 1926. 55 was removed in 1934, and much of the road was replaced by U.S. Highways
52 and
65. The route was paved between Hampton and Farmington as early as 1929. In 1949, State Highway 50 was extended east of Hampton to U.S. 61 near
Miesville along
240th Street East. At one time, State Highway 50 had continued farther west. From 1957 to 1994, the route had continued west of Farmington on present day
Dakota County Highway 50 between
State Highway 3 in Farmington and
Interstate 35 in
Lakeville. This section had also previously been part of old
U.S. Highway 65 from 1934 to 1957. The section of Highway 50 between Hampton and Miesville was paved by 1961. ==Major intersections==