Mississippi Highway 145

US 45 was fully rerouted out of Waynesboro in 2004, and the old alignment became MS 145. MS 145 begins south of town at an intersection with US 45. It heads north through rural and wooded areas before entering the city limits as Mississippi Drive and passing through neighborhoods. The highway then passes through downtown, where it has an intersection with MS 184, before passing through business district and some more neighborhoods. MS 145 passes through more rural areas to have an interchange with US 84 to leave Waynesboro and continue north through wooded areas to come to an end at another intersection with US 45. The entire route of MS 145 is a two-lane highway. ==Boice==

The section of MS 145 near the unincorporated community of Boice, Wayne County is a two-lane road. The highway is not signed with standard highway markers, the only references to the highway number are on small street signs at its two ends at US 45. The highway is not maintained by the Mississippi Department of Transportation (MDOT) past the limits of the intersections with US 45. ==Shubuta==

By 2001, US 45 bypassed Shubuta, and MS 145 was created for US 45's old routing. MS 145 begins south of town at an intersection with US 45. It heads north through rural wooded areas to have an intersection with MS 510 before curving to the northwest to cross a bridge over the Chickasawhay River. The highway then crosses a bridge over some railroad tracks before entering Shubuta and passing straight through downtown along High Street. MS 145 continues northwest to leave Shubuta and pass through farmland before coming to an end at another intersection with US 45. The entire route of MS 145 is a two-lane highway. ==De Soto–Meridian==

Beginning in 1994, US 45 was upgraded to a divided highway outside Meridian. The old alignment continued to be in the state highway system. All of US 45's former routing in Lauderdale County became part of MS 145 in 1998. Two years later, US 45 was realigned onto a new divided highway in Clarke County, and old sections of US 45 became signed as MS 145. MS 145 begins in Clarke County at an intersection with US 45 just south of De Soto. It heads north to pass through the community as a two-lane highway before having an interchange with US 45. The highway leaves De Soto and passes through rural areas for several miles to become concurrent with MS 18 and cross the Chickasawhay River to enter Quitman. MS 145/MS 18 pass through a business district along Archusa Avenue before entering and having an intersection with MS 512, where MS 18 splits off and heads east. MS 145 continues north through neighborhoods, where it has an intersection with MS 513, before winding its way through rural areas for the next several miles, where it crosses US 45 several times, passes by Clarkco State Park, crosses in Lauderdale County, and passes through the community of Wolf Springs. The highway then enters the Meridian city limits and passes through neighborhoods along Roebuck Drive, where it widens to four-lane undivided highway shortly before coming to an end at an interchange with I-20/I-59 (US 11/US 80/MS 19; Exit 53), with the road continuing northwest into downtown as 22nd Avenue. ==Shuqualak==

MS 145 runs for in Shuqualak in Noxubee County, Mississippi. MS 145 begins just south of town at an intersection with US 45. It heads north through rural areas for a short distance to enter Shuqualak at an intersection with MS 21/MS 39. It bypasses downtown along its east side, passing through neighborhoods before leaving Shuqualak and continuing north through rural areas for a few miles before coming to an end at another intersection with US 45. The entire route of MS 145 is a two-lane highway. ==Macon==

By 1998, MS 145 was created after US 45 bypassed the town of Macon. MS 145 begins just south of town at an intersection with US 45. It heads north through wooded areas, running parallel to the Noxubee River, for a few miles to become concurrent with MS 14 and cross a bridge over the river to enter Macon. The highway immediately passes through downtown along Jefferson Street, where MS 14 splits off onto Adams Street, before continuing north through neighborhoods for several miles. MS 145 the leaves Macon and continues through rural areas before coming to an end at another intersection with US 45. The entire route of MS 145 is a two-lane highway. ==Aberdeen==

MS 145 was created in 2000 after US 45 was rerouted to a new divided highway outside Aberdeen. ==Nettleton==

After US 45 was upgraded to a divided highway outside of Nettleton, MS 145 was designated along the former routing. ==Shannon–Booneville==

US 45 was rerouted onto a freeway in Tupelo in 1977, no longer going through downtown Tupelo. The freeway was extended north and south in 1982 and 1984, and more of US 45 was moved. By 1986, the freeway extended as far as Shannon. About ten years later, US 45 was moved to a divided highway for Lee and most of Prentiss County, and the old alignment became MS 145. ==Corinth==

MS 145 was designated as the old routing of US 45 through Corinth in 1998. The portion of the road north of its southern terminus and north of downtown Corinth is not maintained by the state. ==See also==