Beginning at the
interchange with I-29 and 35, Route 210 immediately intersects with the southern terminus of
Route 1 and continues northeast through North Kansas City. It intersects Walker Road in front of NKC Hospital and the
Cerner world headquarters before an interchange with
Chouteau Trafficway right by the
Missouri River. It becomes a limited-access freeway as it enters into
Kansas City proper at
Randolph Bend. It intersects
I-435 and reverts to a four-lane road with stoplights in
Randolph, Missouri. As it reenters Kansas City, it travels 2 miles east through the Missouri River bottoms and then turns northeast 3 miles to its intersection with
Missouri Route 291 at
River Bend, Missouri, which is also part of
Jackson County despite being north of the river. Route 210 exits Kansas City and travels another 7 miles northeasterly before reaching
Missouri City where it turns east, travels 4 more miles, and passes through
Excelsior Springs Junction just south of
Cooley Lake. It then enters
Ray County and travels east-southeast for 3.5 miles, before turning east and passing
Albany and turning northeast towards Richmond. The highway travels northeast 6 miles before reaching its eastern terminus at Route 10 west of Richmond. ==Major intersections==